People Directory

Harald Paganetti, Ph

Director of Physics Research
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Massachusetts General Hospital
Department of Radiation Oncology
100 Blossom Street
Boston, MA 02114
617 726 5847

Research Team website


Director of Physics Research

Current Committee Memberships

Oversight Committee of the Harvard Medical Physics Residency Program

National Council on Radiation Protection and Measurements (NCRP)

International Commission on Radiological Units and Measurements (ICRU)

ASTRO Research Grants Evaluation Sub- Committee

ASTRO Science Council

NRG – Oncology: Chair, RBE White Paper committee

PTCOG-NA: Board of Directors

PTCOG: Research Proposals Sub-Committee

Executive Editorial Board: Physics in Medicine and Biology

Report of Scholarship


4 Books edited

22 Book chapters

294 Peer-reviewed articles (21 sole author, 29 first author, 109 senior author)

H-index: 82


“Proton Therapy Physics”: Ed. Harald Paganetti; Taylor & Francis / CRC Press 2012; ISBN-10: 1439836442

“Principles and Practice of Proton Beam Therapy”: (Eds. Indra J Das and Harald Paganetti); Medical Physics Monograph No. 37; Medical Physics Publishing, Madison, W; ISBN:  978-1-936366-43-9 2015

“Proton Beam Therapy”: Harald Paganetti; IOP Publishing 2017; ISBN: 978-0-7503-1370-4 (ebook)

“Proton Therapy Physics” 2nd edition: Ed. Harald Paganetti; Taylor & Francis / CRC Press 2018; ISBN 9781138626508

Publications in peer-reviewed journals in 2023

  1. McCullum L; Shin J; Xing S; Beekman C; Schuemann J; Hong T; Duda D; Mohan R; Lin S; Correa-Alfonso CM; Domal S; Withrow J; Bolch W; Paganetti H and Grassberger C: Predicting Severity of Radiation Induced Lymphopenia in Individual Patients for Varying Dose Rate and Fractionation Using Dynamic 4D Blood Flow Simulations. International Journal of Radiation Oncology, Biology and Physics 2023
  2. Chamseddine I; Kim Y; De B; El Naqa I; Duda DG; Wolfgang JA; Pursley J; Wo JY; Hong TS; Paganetti H; Koay EJ and Grassberger C: Principal Research Fellow Neural network allows integration of both photon and proton dose distributions with clinical features and improves prediction of radiation-induced hepatic toxicity. International Journal of Radiation Oncology, Biology and Physics 2023
  3. Lee H; Cheon B-W; Feld JW; Grogg K; Perl J; Faddegon B; Min CH; Paganetti H and Schuemann J: TOPAS-imaging: An extension to the TOPAS simulation toolkit for medical imaging systems. Physics in Medicine and Biology 2023
  4. Kim Y; Chamseddine I; Cho Y; Mohan R; Shusharina N; Paganetti H; Lin S; Kim JS; Yoon HI; Cho S and Grassberger C: Neural network based ensemble model to predict radiation induced lymphopenia after concurrent chemo-radiotherapy for non-small cell lung cancer from multiple institutions. Neoplasia 2023
  5. Correa-Alfonso CM; Withrow JA; Domal SJ; President B; Dawson R; McCullum L; Beekman C; Grassberger C; Paganetti H and Bolch WE: Intra-brain vascular models within the ICRP mesh-type adult reference phantoms for applications to internal dosimetry. Physics in Medicine and Biology 2023
  6. Bobić M; Lalonde A; Nesteruk KP; Lee H; Gorissen BL; Bertolet A; Busse P; Chan AW; Winey BA; Sharp GC; Verburg JM; Lomax AJ and Paganetti H: Online adaptation reduces the need for offline replanning due to anatomy changes in head and neck intensity-modulated proton therapy. Clinical and Translational Radiation Oncology 2023
  7. Lalonde A; Bobic M; Sharp GC; Winey B; Paganetti H: Evaluating the effect of anatomical changes and online adaptation on normal tissue complication probability for head and neck intensity modulated proton therapy. Physics in Medicine and Biology 2023
  8. Berrington de González A; Gibson TM; Lee C; Albert PS; Griffin KT; Liu D; Mille MM; Shin J; Bajaj BVM; Flood TE; Gallotto SL; Paganetti H; Ahmed SK; Eaton BR; Indelicato DJ; Milgrom SA; Palmer JD; Baliga S; Poppe MM; Tsang DS; Wong K and Yock TI: The Pediatric Proton and Photon Therapy Comparison Cohort: study design for a multi-center retrospective cohort to investigate subsequent cancers after pediatric radiotherapy. Advances in Radiation Oncology 2023
  9. Bertolet A; Chamseddine I; Paganetti H and Schuemann J: The complexity of DNA damage by radiation follows a Gamma distribution: insights from the Microdosimetric Gamma Model. Frontiers in Oncology 2023
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