An Ionizing Radiation Acoustics Imaging (iRAI) Approach for guided Flash Radiotherapy

A postdoctoral position is available in the Optimization Laboratory and Multi-Scale Monte Carlo Modeling Laboratory of the Physics Division in the Department of Radiation Oncology at the Massachusetts General Hospital (MGH) and Harvard Medical School in Boston.

The postdoctoral fellow will work on ultra-fast image-guided radiotherapy with proton beams, specifically for FLASH treatments. Ultrasound imaging systems will be used for both anatomic imaging and visualization of the radiation dose with ionizing radiation acoustic imaging (iRAI). The project is funded by the National Cancer Institute, and embedded in a national collaboration with the Moffitt Cancer Center and the University of Michigan. The successful candidate will be appointed as a Research Fellow at the Harvard Medical School.

The responsibilities fall in the following areas:

  • Optimizing the pulse structure of the beam for maximum yield of the radiation acoustic signal;
  • Characterization of the iRAI system via Monte Carlo simulations;
  • Experimental testing in the proton beamline at MGH using phantoms;
  • Development of optimal control strategies, and optimal stopping of the treatment delivery if necessary.


Ideal candidates have a Ph.D. in applied physics, applied math, computer science, operations research or related area and are highly motivated to apply the profound skills and theoretical knowledge that they acquired in their respective fields of study to improve clinical cancer medicine. They are algorithmic thinkers and problem solvers, eager to learn and address the challenges of radiation oncology physics. Excellent verbal and written communication skills as well as willingness to collaborate closely with the partners in other centers are essential.


The postdoctoral fellow will primarily work in the Radiation Biophysics Division of Massachusetts General Hospital and will be part of an inspiring research environment as a member of a collegial, diverse, and highly motivated research team, consisting of medical physicists, computer scientists, operation research experts, and clinical oncologists.

To Apply:

  • Statement describing areas of research interest and goals for the postdoctoral fellowship
  • Curriculum vitae with list of publications
  • Contact information of 3 persons serving as references

Please email these documents to:
Thomas Bortfeld, Ph.D.
Andres Soriano Professor, Harvard Medical School
Chief, Division of Radiation Biophysics, Department of Radiation Oncology
Massachusetts General Hospital
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Application deadline: November 30, 2022