Lab Head: Clemens Grassberger, PhD

The majority of patients treated with radiation therapy also receive other treatments, ranging from surgery and chemotherapy to recent additions like targeted agents and immunotherapeutic approaches. In the Radiation-Drug Treatment Design Lab we develop and apply methodologies to describe the interaction of these systemic therapies with radiation in the context of specific clinical indications, with the aim to design rational clinical trials and patient-specific treatments.

Research Areas

• Impact of radiotherapy on lymphocytes & patient immunity
• How to integrate radiotherapy with checkpoint inhibitors
• Resistance development to targeted agents (EGFR inhibitors) & role of radiotherapy
• Mechanistic and data-driven modeling to predict treatment outcome

Recent News

• Wonmo Sung's award-winning (best translational research, ASTRO 2019) now published in Radiotherapy & Oncology: https://authors.elsevier.com/a/1bVcBcA0-4Oqx
• Abdelkhalek Hammi paper on calculating dose to the circulating blood during brain radiation now out in PMB; featured in best abstracts at ICCR 2019 & AAPM 2019 -->  https://iopscience.iop.org/article/10.1088/1361-6560/ab6c41/meta

Funding

• 2 NIH/NCI R21s
• CHEST Foundation
• MGH ECOR Funding

 

Project Opportunities: to find out about opportunities in our group, have a look at our list of open projects --> here

 

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