Publications

Predicting patient-specific dosimetric benefits of proton therapy for skull-base tumors using a geometric knowledge-based method

Authors: Hall DC, Trofimov AV, Winey BA, Liebsch NJ, Paganetti H
Journal: International Journal of Radiation Oncology * Biology * Physics
Volume: 97
Issue: 5
Pages: 1087–1094
Year: 2017

Sampling random directions within an elliptical cone

Authors: Hall DC
Published in: Computer Physics Communications
Volume: 219
Pages: 87-90
Year: 2017

Validation of nuclear models in Geant4 using the dose distribution of a 177 MeV proton pencil beam

Authors: Hall DC, Makarova A, Paganetti H, Gottschalk B
Journal: Physics in Medicine and Biology
Volume: 61
Issue: 1
Pages: N1
Year: 2016

A Greedy reassignment algorithm for the PBS minimum monitor unit constraint

Authors: Lin, Yuting, Kooy, Hanne, Craft, David, Depauw, Nicolas, Flanz, Jacob, Clasie, Benjamin
Journal: Physics in Medicine and Biology
Volume: 61
Issue: 12
Pages: 4664-4678
Year: 2016

Investigation of cone-beam CT image quality trade-off for image-guided radiation therapy

Authors: Bian, JG (Bian, Junguo)[ 1,2 ] , Sharp, GC (Sharp, Gregory C.)[ 2,3,4 ] , Park, YK (Park, Yang-Kyun)[ 2,3,4 ] , Ouyang, JS (Ouyang, Jinsong)[ 1,2 ] , Bortfeld, T (Bortfeld, Thomas)[ 2,3,4 ] , El Fakhri, G (El Fakhri, Georges)[ 1,2 ]
Published in: PHYSICS IN MEDICINE AND BIOLOGY Volume: 61 Issue: 9 Pages: 3317-3346 Published: MAY 7 2016
Year: 2016

Radiation oncology in the era of precision medicine

Authors: Baumann, M (Baumann, Michael)[ 1,2,3,4,5,6,7,8 ] , Krause, M (Krause, Mechthild)[ 1,2,3,4,5,6,7,8 ] , Overgaard, J (Overgaard, Jens)[ 9 ] , Debus, J (Debus, Juergen)[ 7,10,11,12,13 ] , Bentzen, SM (Bentzen, Soren M.)[ 14,15 ] , Daartz, J (Daartz, Juliane)[ 16,17 ] , Richter, C (Richter, Christian)[ 1,2,3,4,5,6,7 ] , Zips, D(Zips, Daniel)[ 7,18,19,20 ] , Bortfeld, T (Bortfeld, Thomas)[ 16,17 ]
Published in: NATURE REVIEWS CANCER Volume: 16 Issue: 4 Pages: 234-249 Published: APR 2016
Year: 2016

A Prospective Comparison of the Effects of Interfractional Variations on Proton Therapy and Intensity Modulated Radiation Therapy for Prostate Cancer

Authors: Moteabbed, M (Moteabbed, Maryam)[ 1 ] , Trofimov, A (Trofimov, Alexei), Sharp, GC (Sharp, Gregory C.), Wang, Y (Wang, Yi), Zietman, AL (Zietman, Anthony L.), Efstathiou, JA (Efstathiou, Jason A.), Lu, HM (Lu, Hsiao-Ming)
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 444-453 Published: MAY 1 2016
Year: 2016

Reassessment of the Necessity of the Proton Gantry: Analysis of Beam Orientations From 4332 Treatments at the Massachusetts General Hospital Proton Center Over the Past 10 Years

Authors: Yan, SS (Yan, Susu)[ 1 ] , Lu, HM (Lu, Hsiao-Ming)[ 1 ] , Flanz, J (Flanz, Jay)[ 1 ] , Adams, J (Adams, Judith)[ 1 ] , Trofimov, A (Trofimov, Alexei)[ 1 ] ,Bortfeld, T (Bortfeld, Thomas)[ 1 ]
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 224-233 Published: MAY 1 2016
Year: 2016

Can We Advance Proton Therapy for Prostate? Considering Alternative Beam Angles and Relative Biological Effectiveness Variations When Comparing Against Intensity Modulated Radiation Therapy

Authors: Underwood, T (Underwood, Tracy)[ 1,2 ] , Giantsoudi, D (Giantsoudi, Drosoula)[ 1 ] , Moteabbed, M (Moteabbed, Maryam)[ 1 ] , Zietman, A (Zietman, Anthony)[ 1 ] , Efstathiou, J (Efstathiou, Jason)[ 1 ] , Paganetti, H (Paganetti, Harald)[ 1 ] , Lu, HM (Lu, Hsiao-Ming)[ 1 ]
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 454-464 Published: MAY 1 2016
Year: 2016

Incidence of CNS Injury for a Cohort of 111 Patients Treated With Proton Therapy for Medulloblastoma: LET and RBE Associations for Areas of Injury

Authors: Giantsoudi, D (Giantsoudi, Drosoula)[ 1 ] , Sethi, RV (Sethi, Roshan V.)[ 1 ] , Yeap, BY (Yeap, Beow Y.)[ 2 ] , Eaton, BR (Eaton, Bree R.)[ 1 ] , Ebb, DH(Ebb, David H.)[ 3 ] , Caruso, PA (Caruso, Paul A.)[ 4 ] , Rapalino, O (Rapalino, Otto)[ 4 ] , Chen, YLE (Chen, Yen-Lin E.)[ 1 ] , Adams, JA (Adams, Judith A.)[ 1 ] , Yock, TI (Yock, Torunn I.)[ 1 ] , Tarbell, NJ (Tarbell, Nancy J.)[ 1 ] , Paganetti, H (Paganetti, Harald)[ 1 ] , MacDonald, SM (MacDonald, Shannon M.)[ 1 ]
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 287-296 Published: MAY 1 2016
Year: 2016

Impact of Spot Size and Beam-Shaping Devices on the Treatment Plan Quality for Pencil Beam Scanning Proton Therapy

Authors: Moteabbed, M (Moteabbed, Maryam)[ 1 ] , Yock, TI (Yock, Torunn I.), Depauw, N (Depauw, Nicolas), Madden, TM (Madden, Thomas M.), Kooy, HM (Kooy, Hanne M.), Paganetti, H (Paganetti, Harald)
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 190-198 Published: MAY 1 2016
Year: 2016

Disruption of SLX4-MUS81 Function Increases the Relative Biological Effectiveness of Proton Radiation

Authors: Liu, Q (Liu, Qi)[ 1 ] , Underwood, TSA (Underwood, Tracy S. A.)[ 2 ] , Kung, J (Kung, Jong)[ 2 ] , Wang, M (Wang, Meng)[ 1 ] , Lu, HM (Lu, Hsiao-Ming)[ 2 ] ,Paganetti, H (Paganetti, Harald)[ 2 ] , Held, KD (Held, Kathryn D.)[ 1 ] , Hong, TS (Hong, Theodore S.)[ 1 ] , Efstathiou, JA (Efstathiou, Jason A.)[ 1 ] , Willers, H(Willers, Henning)[ 1 ]
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 78-85 Published: MAY 1 2016
Year: 2016

Variable Proton Relative Biological Effectiveness: How Do We Move Forward?

Authors: Underwood, T (Underwood, Tracy)[ 1,2 ] , Paganetti, H (Paganetti, Harald)[ 1 ]
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 95 Issue: 1 Pages: 56-58 Published: MAY 1 2016
Year: 2016

Dose assessment for the fetus considering scattered and secondary radiation from photon and proton therapy when treating a brain tumor of the mother.

Authors: Geng, Changran, Moteabbed, Maryam, Seco, Joao, Gao, Yiming, George Xu, X, Ramos-Mendez, Jose, Faddegon, Bruce, Paganetti, Harald
Published in: Physics in medicine and biology Volume:61 Issue:2 Pages:683-95 Published:2016-Jan-21 (Epub 2015 Dec 30)
Year: 2016

Multi-criteria optimization achieves superior normal tissue sparing in a planning study of intensity-modulated radiation therapy for RTOG 1308-eligible non-small cell lung cancer patients

Authors: Kamran, SC (Kamran, Sophia C.)[ 1 ] , Mueller, BS (Mueller, Birgit S.)[ 2,3 ] , Paetzold, P (Paetzold, Peter)[ 4 ] , Dunlap, J (Dunlap, Joseph)[ 4 ] , Niemierko, A (Niemierko, Andrzej)[ 4,5 ] , Bortfeld, T (Bortfeld, Thomas)[ 4 ] , Willers, H (Willers, Henning)[ 4 ] , Craft, D (Craft, David)[ 4 ]
Published in: RADIOTHERAPY AND ONCOLOGY Volume: 118 Issue: 3 Pages: 515-520 Published: MAR 2016
Year: 2016

Assessing the radiation-induced second cancer risk in proton therapy for pediatric brain tumors: the impact of employing a patient-specific aperture in pencil beam scanning

Authors: Geng, CR (Geng, Changran)[ 1,3 ] , Moteabbed, M (Moteabbed, Maryam)[ 1,2 ] , Xie, YH (Xie, Yunhe)[ 1 ] , Schuemann, J (Schuemann, Jan)[ 1,2 ] , Yock, T(Yock, Torunn)[ 1,2 ] , Paganetti, H (Paganetti, Harald)[ 1,2 ]
Published in: PHYSICS IN MEDICINE AND BIOLOGY Volume: 61 Issue: 1 Pages: 12-22 Published: JAN 7 2016
Year: 2016

PBS machine interlocks using EWMA

Authors: Clasie, BM (Clasie, Benjamin M.)[ 1 ] , Kooy, HM (Kooy, Hanne M.), Flanz, JB (Flanz, Jacob B.)
Published in: PHYSICS IN MEDICINE AND BIOLOGY
Year: 2016

Roadmap to Clinical Use of Gold Nanoparticles for Radiation Sensitization

Authors: Schuemann, J (Schuemann, Jan)[ 1,2 ] , Berbeco, R (Berbeco, Ross)[ 2,3 ] , Chithrani, DB (Chithrani, Devika B.)[ 4 ] , Cho, SH (Cho, Sang Hyun)[ 5,6 ] ,Kumar, R (Kumar, Rajiv)[ 7,8 ] , McMahon, SJ (McMahon, Stephen J.)[ 1,2,9 ] , Sridhar, S (Sridhar, Srinivas)[ 7,8 ] , Krishnan, S (Krishnan, Sunil)[ 10 ]
Published in: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Year: 2016

Optimising element choice for nanoparticle radiosensitisers

Authors: McMahon, SJ (McMahon, Stephen J.)[ 1,2 ] , Paganetti, H (Paganetti, Harald)[ 1,2 ] , Prise, KM (Prise, Kevin M.)[ 3 ]
Published in: NANOSCALE McMahon, SJ (McMahon, Stephen J.)[ 1,2 ] , Paganetti, H (Paganetti, Harald)[ 1,2 ] , Prise, KM (Prise, Kevin M.)[ 3 ] Published: 2016
Year: 2016

Automated Monte Carlo simulation of proton therapy treatment plans

Authors: Verburg JM, Grassberger C, Dowdell S, Schuemann J, Seco J, Paganetti H
Journal: Technology in Cancer Research & Treatment
Year: 2015