Automated interactive definition of the clinical target volume in radiation oncology

Position Description:
A postdoctoral position is available in the Optimization Laboratory of the Physics Division in the Department of Radiation Oncology at the Massachusetts General Hospital in Boston.

The postdoctoral fellow will join an active academic-industry project, funded by the National Cancer Institute, to address one of the grand challenges in the field of radiation oncology: the definition of the clinical tumor target volume (CTV) . The project is embedded in an international collaboration between centers in the US and Europe. The industrial partner is RaySearch AB in Stockholm, Sweden. The successful candidate will be appointed as a research fellow at the Harvard Medical School.

The responsibilities fall in the following areas. The candidate will be able to focus on a subset of these areas based on personal interests, skills and preferences.

  • Automated segmentation of obstacles to tumor spread from medical images
  • Modeling of anisotropic tumor spread
  • Automated expansion from the gross tumor volume to CTV using fast marching and diffusion models (PDE solver)
  • Parametric editing of CTV contours
  • Integration of interactive parametric contour editing in existing treatment plan optimization algorithms
  • Modeling of uncertainties

For a review of previous work on the subject, see here

Qualifications:
Ideal candidates have a Ph.D. in applied physics, applied math, computer science, operations research or related area and are highly motivated to apply the profound skills and theoretical knowledge that they acquired in their respective fields of study to improve clinical cancer medicine. They are algorithmic thinkers and problem solvers, eager to learn and address the clinical challenges of radiation oncology. Strong programming skills in Python are essential. Excellent verbal and written communication skills as well as willingness to collaborate in an interdisciplinary environment are important.

Environment:
The postdoctoral fellow will primarily work in the Radiation BioPhysics Division of Massachusetts General Hospital and will be part of an inspiring research environment as a member of a collegial, diverse, and highly motivated research team, consisting of medical physicists, computer scientists, operation research experts, and clinical oncologists.

To Apply:

  • Statement describing areas of research interest and goals for the postdoctoral fellowship
  • Curriculum vitae with list of publications
  • Contact information of 3 persons serving as references

Please email these documents to:
Thomas Bortfeld, Ph.D.
Professor and Director, Division of Radiation Biophysics, Department of Radiation Oncology
Massachusetts General Hospital and Harvard Medical School
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Application deadline: February 25, 2022