David Craft, Ph.D.



Assistant Professor, Harvard Medical School
Massachusetts General Hospital
Department of Radiation Oncology

E-mail: dcraft(at)alum.mit.edu

Education and Degrees:

B.Sc.: Brown University, Mechanical Engineering (solid mechanics), Summa Cum Laude, 1996
Ph.D.: Massachusetts Institute of Technology, Operations Research, 2004

Areas of Interest:

Multi-criteria optimization in radiation therapy
Mathematics and statistics


Shared data for intensity modulated radiation therapy (IMRT) optimization research: the CORT dataset GigaScience, 2015.
Three-dimensional conformal planning with low-segment multicriteria intensity modulated radiation therapy optimization, Kahn, Craft.  GigaScience, 2015.
Optimization approaches to volumetric modulated arc therapy planningUnkelbach, Bortfeld, Craft, et al, Med Phys, 2015.
Plan averaging for multicriteria navigation of sliding window IMRT and VMAT, Med Phys, 2014.
Multi-criteria optimization methods in radiation therapy planning: a review of technologies and directions. Springer, submitted.
Guaranteed Epsilon-Optimal Solutions with the Minimum Number of Beams for Stereotactic Body Radiation Therapy, Yarmand, Winey, Craft. PMB (2013)
A hybrid approach to beam angle optimization in intensity-modulated radiation therapy  Bertsimas, Cacchiani, Craft, Nohadani. Computers and Operations Research (2013).
Maximizing dosimetric benefits of IMRT in the treatment of localized prostate cancer through multicriteria optimization planning, Medical Dosimetry, 2013.
Deliverable navigation for multicriteria step and shoot IMRT treatment planning, Physics in Medicine and Biology, 2013.
The dependence of optimal fractionation schemes on the spatial dose distribution, Physics in Medicine and Biology, 2013.
Exploring Trade-off s between VMAT Treatment Quality and Delivery Efficiency, Salari et al, Physics in Medicine and Biology, 2012.
Optimal partial-arcs in VMAT treatment planning, Jeremiah Wala, Ehsan Salari, Wei Chen and David Craft, Physics in Medicine and Biology, 2012.
Including robustness in multi-criteria optimization for intensity-modulated proton therapy, Wei Chen, Jan Unkelbach, Alexei Trofimov, Thomas Madden, Hanne Kooy, Thomas Bortfeld and David Craft, 2012 Phys. Med. Biol. 57.
Multicriteria VMAT optimization, to appear in Medical Physics, 2012 Improved planning time and plan quality through multicriteria optimization for intensity-modulated radiotherapy. International Journal of Radiation Oncology * Biology * Physics, 2011
A fast optimization algorithm for multicriteria intensity modulated proton therapy planning. Chen, Herman, Craft, Madden, Zhang, Kooy. Medical Physics, 2010; 37(9).
Simultaneous navigation of multiple Pareto surfaces, with an application to multicriteria IMRT planning with multiple beam angle configurations. Medical Physics 2010;37(2).
Calculating and Controlling the Error of Discrete Representations of Pareto Surfaces in Convex Multi-Criteria Optimization. Physica Medica. 2010.
Multicriteria Optimization in IMRT Treatment Planning For Locally Advanced Cancer of the Pancreatic Head. International Journal of Radiation Oncology * Biology * Physics, 2008;72(4):1208-1214.
Evaluating Target Cold Spots By the Use of Tail EUDs. International Journal of Radiation Oncology * Biology * Physics, 2008;71:880-889.
How Many Plan Are Needed in an IMRT Multi-Objective Plan Database. Physics in Medicine and Biology. 2008;53:2785-2796.
An approach for practical multiobjective IMRT treatment planning, Int J Radiat Oncol Biol Phys. 2007;69(5):1600-1607
The tradeoff between treatment plan quality and intensity field complexity in IMRT, Red Journal, volume 67 number 5, April 2007
Local beam angle optimization with linear programming and gradient search. Phys. Med. Biol. -- March 2007 -- Vol. 52, pp. N127-N135.
Dose-volume objectives in multi-criteria optimization (Halabi et al., Phys. Med. Biol. -- August, 2006 -- Volume 51, pp. 3809-3818)
Approximating convex Pareto surfaces in multiobjective radiotherapy planning (Medical Physics -- September 2006 -- Volume 33, Issue 9, pp. 3399-3407)
Exploration of tradeoffs in intensity-modulated radiotherapy (2005, Physics in Medicine and Biology)
Maximizing Operating Room and Recovery Room Capacity in an Era of Constrained Resources, Arch Surg. 2006;141:389-395.
Surgeon Profiling: A Key to Optimum Operating Room Use, Arch Surg. 2007;142:365-370
Ph.D. Thesis: Local energy management through mathematical modeling and optimization
Analyzing Bioterror Response Logistics: The Case of Anthrax (May 2005, Management Science, Volume 51, Number 5)
Analyzing bioterror response logistics: The case of smallpox (2003, Mathematical Biosciences, Volume 185 Issue 1)
Emergency response to a smallpox attack: The case for mass vaccination (2002, Proceedings of the National Academy of Sciences)          - Work discussed in the New York Times, July 9, 2002
Emergency Response to an Anthrax Attack (2003, Proceedings of the National Academy of Sciences)
A Mathematical Model of the Impact of Novel Treatments on the A-Beta Burden in the Alzheimer's Brain, CSF and Plasma (2001, Bulletin of Mathematical Biology)
Bower, A.F. and Craft, D. (1998) Analysis of failure mechanisms in the interconnect lines of microelectronic circuits. Fatigue & Fracture of Engineering Materials & Structures 21 611-630