Thomas Bortfeld, Ph.D.

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Professor, Harvard Medical School 
Director, Physics Division
 
Massachusetts General Hospital, Department of Radiation Oncology
Francis H. Burr Proton Therapy Center, Rm 106, 30 Fruit St, Boston, MA 02114

 

Phone: (617) 643 2255
Fax: (617) 724 9532
E-mail: tbortfeld(at)mgh.harvard.edu

 
Detailed Curriculum Vitae: download PDF file

Education and Degrees:

MS (Diploma): University of Heidelberg , Germany, 1988, Physics
Ph.D.: University of Heidelberg , Germany, 1990, Applied Physics
Habilitation: University of Heidelberg, Germany, 1995, Physics - download PDF file

Areas of Interest:

  • Optimization, Multi-Criteria Optimization 
  • Therapy Imaging
  • Proton Radiotherapy
  • Dynamics of Cancer Treatment

Recent Honors:

Fellow, American Association of Physicists in Medicine, 2009
12th annual Suntharalingam Lecture, 2009
Recent keynote lectures
- PTCOG Essen, Germany 2013;
- FIRST conference Sapporo, Japan 2013  

Recent Talks:

Harvard Applied Physics Colloquium: Physics against Cancer 

In the News:

  1. A pioneering approach to cancer treatment
     http://physicsworld.com/cws/article/multimedia/2013/mar/14/a-pioneering-approach-to-cancer-treatment
  2. Targeting tumours 
  3. Proton therapy teams up with PET imaging

Editorial Boards: 

 Physics in Medicine and Biology (international advisory board)

 Radiotherapy and Oncology

 European Journal of Medical Physics  

 Medizinische Physik (advisory board)

Selected Recent Publications (total of more than 150 peer-reviewed papers):

Periodicals:

  • Verburg JM, Riley K, Bortfeld T, Seco J. Energy- and time-resolved detection of prompt gamma-rays for proton range verification. Phys Med Biol. 2013 Oct 21;58(20):L37-49.
  • Safai S, Trofimov A, Adams JA, Engelsman M, Bortfeld T. The rationale for intensity-modulated proton therapy in geometrically challenging cases. Phys Med Biol. 2013 Sep 21;58(18):6337-53.
  • Flanz J, Bortfeld T. Evolution of technology to optimize the delivery of proton therapy: the third generation. Semin Radiat Oncol. 2013 Apr;23(2):142-8.
  • Yuan Y, Andronesi OC, Bortfeld TR, Richter C, Wolf R, Guimaraes AR, Hong TS, Seco J. Feasibility study of in vivo MRI based dosimetric verification of proton end-of-range for liver cancer patients. Radiother Oncol. 2013 Mar;106(3):378-82.
  • Unkelbach J, Craft D, Salari E, Ramakrishnan J, Bortfeld T. The dependence of optimal fractionation schemes on the spatial dose distribution. Phys Med Biol. 2013 Jan 7;58(1):159-67.
  • Craft D, McQuaid D, Wala J, Chen W, Salari E, Bortfeld T. Multicriteria VMAT optimization. Med Phys. 2012; 39(2):686-96.
  • Ramakrishnan J, Craft D, Bortfeld T, Tsitsiklis JN. A dynamic programming approach to adaptive fractionation. Phys Med Biol. 2012; 57(5):1203-16.
  • Chen W, Unkelbach J, Trofimov A, Madden T, Kooy H, Bortfeld T, Craft D Including robustness in multi-criteria optimization for intensity-modulate proton therapy. Phys Med Biol. 2012;57(3):591-608.
  • Craft DL, Hong TS, Shih HA, Bortfeld TR. Improved Planning Time and Plan Quality Through Multicriteria Optimization for Intensity-Modulated Radiotherapy. Int J Radiat Oncol Biol Phys. 2012; 82(1):e83-90.
Special Issues: 
  • Controversies in Proton Therapy. Brada M, Bortfeld T eds. Seminars in Radiation Oncology. 2013;23(2):75-153.